IGF-I LC/MS/MS

$ 159.00

Doctor’s order included No insurance needed No additional lab fees

Pricing is all-inclusive. No surprise lab or collection fees. Orders and results are sent electronically.

IGF-1 LC/MS/MS Blood Test

Insulin-Like Growth Factor 1 Test for Growth Hormone and Pituitary Function Screening

The IGF-1 LC/MS/MS Blood Test measures Insulin-Like Growth Factor 1, also called IGF-1 or Somatomedin C, in the blood.

IGF-1 is produced mainly by the liver and other tissues in response to growth hormone, also called GH. Because IGF-1 levels are more stable throughout the day than growth hormone levels, IGF-1 is often used as an indirect marker of average growth hormone activity.

This test may be useful when a healthcare provider wants to evaluate possible growth hormone deficiency, growth hormone excess, pituitary function, or provider-directed endocrine monitoring.

This service provides access to lab testing only. It is intended as a screening and monitoring tool and does not diagnose, treat, or replace care from a licensed healthcare provider.

Measures IGF-1, also called Insulin-Like Growth Factor 1
LC/MS/MS testing method
May support growth hormone and pituitary evaluation
Doctor's order included
No insurance required


⏱ Typical turnaround: results are usually emailed in 1–3 days.

What This Test Measures

Insulin-Like Growth Factor 1

This blood test measures IGF-1, a hormone-like protein involved in growth, metabolism, tissue maintenance, and bone health.

  • Test name: IGF-1 LC/MS/MS
  • Also known as: Insulin-Like Growth Factor 1, Somatomedin C, IGF-I
  • Sample type: Blood
  • Purpose: Growth hormone and pituitary function screening
  • Common use: Provider-directed endocrine evaluation

Why Order an IGF-1 Test?

  • Growth hormone deficiency evaluation - IGF-1 may be low when growth hormone activity is reduced.
  • Growth hormone excess evaluation - IGF-1 may be elevated in conditions associated with excess growth hormone activity.
  • Pituitary function review - May be ordered with other pituitary hormone tests.
  • Follow-up to abnormal hormone results - May help support a broader endocrine evaluation.
  • Growth or development concerns - May be used when a provider is evaluating growth-related concerns.
  • Provider-directed monitoring - Useful when your healthcare provider specifically requests IGF-1 testing.

Who May Consider This Test?

This test may be appropriate for:

  • Individuals whose healthcare provider requested an IGF-1 blood test
  • People being evaluated for possible growth hormone deficiency
  • People being evaluated for possible growth hormone excess
  • Patients undergoing pituitary function evaluation
  • Individuals being monitored for endocrine or growth hormone-related conditions
  • Customers who want doctor-ordered IGF-1 testing without using insurance

IGF-1 and Growth Hormone

Growth hormone levels can change throughout the day, making direct growth hormone interpretation challenging in many situations.

IGF-1 is more stable in the blood and can provide useful information about average growth hormone activity over time.

IGF-1 is not usually interpreted by itself. Your provider may also order growth hormone stimulation or suppression testing, pituitary hormones, thyroid testing, prolactin, FSH, LH, cortisol, or imaging depending on your situation.


Age and Sex Matter

IGF-1 levels vary by age and sex. Levels are typically higher during puberty and tend to decline with age.

Your result should be interpreted using the appropriate reference range for your age and sex.


Important Biotin Warning

If you take biotin, also known as vitamin B7, vitamin B8, vitamin H, or coenzyme R, ask your healthcare provider whether you should stop biotin before testing.

Biotin may interfere with certain hormone lab testing methods and could affect results.


Important Symptom Warning

If you have severe headache, sudden vision changes, fainting, severe weakness, chest pain, shortness of breath, severe swelling, confusion, or any urgent medical concern, seek medical care promptly.

Do not use this IGF-1 test as a substitute for urgent medical evaluation, diagnosis, or treatment.


Important: Screening Only

LabReqs and SchoolTiters provide access to lab testing. We do not diagnose growth hormone deficiency, acromegaly, pituitary tumors, endocrine disease, growth disorders, or any medical condition.

Results should be reviewed with a licensed healthcare provider, endocrinologist, pediatric endocrinologist, or other qualified clinician.


Important Limitations

  • This test does not diagnose a medical condition by itself.
  • IGF-1 results must be interpreted with age, sex, symptoms, nutrition status, medical history, and other hormone tests.
  • Normal IGF-1 does not rule out every growth hormone or pituitary disorder.
  • Abnormal IGF-1 may require repeat testing, growth hormone stimulation or suppression testing, or additional endocrine evaluation.
  • This test does not include growth hormone, IGFBP-3, prolactin, cortisol, FSH, LH, thyroid testing, or imaging unless ordered separately.

Before Ordering

  • Confirm whether your provider requested IGF-1 alone or additional pituitary hormone testing.
  • Tell your provider about medications, supplements, hormone therapy, nutrition status, and medical history.
  • If testing is for a child or adolescent, confirm whether the provider needs pediatric reference interpretation or Z-score reporting.
  • If you take biotin, ask whether to stop it before testing.
  • If you are unsure whether IGF-1 testing is right for you, ask your healthcare provider before ordering.

How It Works

  1. Order online.
  2. Receive your lab order. A doctor's order is included.
  3. Visit a participating lab location.
  4. Complete a simple blood draw.
  5. Receive your results. Result timing may vary by lab, location, and processing requirements.

Why Choose This Test?

Measures IGF-1, also called Somatomedin C
Useful for provider-directed growth hormone and pituitary evaluation
LC/MS/MS testing method
Doctor's order included
No insurance needed
Convenient online ordering


Frequently Asked Questions

What does IGF-1 measure?

IGF-1 measures Insulin-Like Growth Factor 1, a hormone-like protein regulated mainly by growth hormone and nutrition.

Is IGF-1 the same as growth hormone?

No. IGF-1 is not growth hormone. It is produced in response to growth hormone and is often used as an indirect marker of growth hormone activity.

Why would my provider order IGF-1?

Your provider may order IGF-1 to help evaluate possible growth hormone deficiency, growth hormone excess, pituitary function, or endocrine monitoring.

Does this test diagnose growth hormone problems?

No. IGF-1 provides lab information only. Diagnosis usually requires clinical evaluation and may require additional testing.

Do I need to fast?

Fasting is usually not required unless your healthcare provider gives you different instructions.

Does age affect IGF-1?

Yes. IGF-1 levels vary significantly by age and sex, so results should be interpreted using the correct reference range.

Is a doctor's order included?

Yes. A doctor's order is included with this lab test.


Order Your IGF-1 LC/MS/MS Blood Test

Use this test when you need IGF-1 testing for provider-directed growth hormone, pituitary, endocrine, growth-related, or metabolic evaluation.

Order your IGF-1 LC/MS/MS Blood Test today.

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IGF-I LC/MS/MS
$ 159.00
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